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Ionotropic glutamate receptor that functions as a cation permeable ligand-gated ion channel, gated by L-glutamate as well as the glutamatergic agonist kainic acid. L-glutamate functions as an excitatory neurotransmitter at numerous synapses during the central anxious method. Binding from the excitatory neurotransmitter L-glutamate induces a conform